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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNKS2
All Species:
38.79
Human Site:
Y1155
Identified Species:
71.11
UniProt:
Q9H2K2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2K2
NP_079511.1
1166
126918
Y1155
Y
P
E
Y
L
I
T
Y
Q
I
M
R
P
E
G
Chimpanzee
Pan troglodytes
XP_001137443
1327
142033
Y1308
Y
P
E
Y
L
I
T
Y
Q
I
M
K
P
E
A
Rhesus Macaque
Macaca mulatta
XP_001090358
1327
142132
Y1308
Y
P
E
Y
L
I
T
Y
Q
I
M
K
P
E
A
Dog
Lupus familis
XP_534962
1316
141794
Y1305
Y
P
E
Y
L
I
T
Y
Q
I
M
R
P
E
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_001157107
1166
126725
Y1155
Y
P
E
Y
L
I
T
Y
Q
I
V
R
P
E
G
Rat
Rattus norvegicus
NP_001101077
1166
126761
Y1155
Y
P
E
Y
L
I
T
Y
Q
I
V
R
P
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508887
1320
142724
Y1301
Y
P
E
Y
L
I
T
Y
Q
I
V
K
P
D
A
Chicken
Gallus gallus
Q5F478
990
107379
A983
N
G
P
R
T
S
S
A
T
D
V
Q
K
E
E
Frog
Xenopus laevis
NP_001088420
1303
140252
Y1284
Y
P
E
Y
L
I
T
Y
Q
I
M
K
P
E
T
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
G1060
G
Y
G
K
D
R
H
G
A
T
I
G
L
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651410
1181
127927
Y1165
Y
P
E
Y
L
I
T
Y
Q
I
V
K
P
D
D
Honey Bee
Apis mellifera
XP_396483
1166
127309
Y1148
Y
P
E
Y
L
I
T
Y
Q
I
A
R
P
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186587
1157
126547
F1147
F
P
E
Y
L
I
T
F
Q
I
V
K
P
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.5
72.5
87.9
N.A.
97.2
97.2
N.A.
72.5
24
73.1
23.3
N.A.
65.3
70.6
N.A.
69.5
Protein Similarity:
100
80.3
80.3
88.2
N.A.
98.8
99
N.A.
80.5
40.3
81.3
38.9
N.A.
79.8
83
N.A.
83.1
P-Site Identity:
100
86.6
86.6
100
N.A.
93.3
93.3
N.A.
73.3
6.6
86.6
6.6
N.A.
73.3
80
N.A.
60
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
93.3
26.6
93.3
20
N.A.
93.3
86.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
0
31
8
% D
% Glu:
0
0
85
0
0
0
0
0
0
0
0
0
0
62
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
0
8
0
0
0
8
0
0
39
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
85
0
0
0
85
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
47
8
0
0
% K
% Leu:
0
0
0
0
85
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
85
8
0
0
0
0
0
0
0
0
0
85
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
85
0
0
8
0
8
8
% Q
% Arg:
0
0
0
8
0
8
0
0
0
0
0
39
0
0
0
% R
% Ser:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
8
0
85
0
8
8
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
77
8
0
85
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _